In contrast, men who consumed a similarly moderate amount of beer for the same period exhibited a significant increase in basophils alone. Yes, chronic alcohol abuse can lead to long-term negative effects on the immune system, making individuals more susceptible to infections and diseases. Furthermore, alcohol consumption dehydrates our bodies, which affects the ability of our mucous membranes to trap and eliminate viruses.
Alcohol addiction delivers a devastating one-two punch by both hindering the body’s defenses and leaving organs vulnerable to disease. In addition to laboratory studies confirming the impact of alcohol consumption on the innate immune system, several studies have looked at how heavy drinking can when you use/abuse alcohol your resistance to colds increases alter plasma cytokine levels. To this end, one study analyzed IL-10, IL-6, IL-18, and tumor necrosis factor α (TNF-α) levels in 25 non-treating seeking heavy drinkers after they had consumed an alcoholic drink. The researchers reported significant reductions in the TNF-α levels three and six hours after the alcohol consumption. Years of excessive alcohol intake can overwhelm and permanently damage immune defenses, making full recovery unlikely.

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Finally, remember that this phase is a testament to your body’s resilience. Every cold, cough, or sniffle is evidence that your immune system is rebuilding itself. For those in recovery, especially individuals over 30 whose immune systems may already be slower to respond, this process is particularly crucial. By understanding and addressing these temporary vulnerabilities, you’re not just quitting alcohol—you’re actively restoring your body’s ability to protect itself. Patience and self-care during this period will pave the way for a stronger, healthier future.
How alcohol affects the innate immune system
For heavy drinkers, defined as consuming 4-5 drinks per day or more, the risk escalates significantly, as their bodies are in a near-constant state of alcohol-induced stress. Comparing non-drinkers to heavy drinkers highlights the stark difference in respiratory outcomes. Research indicates that heavy drinkers (consuming 8+ drinks per week for women and 15+ for men) experience colds 2-3 times more frequently than non-drinkers. They also report longer recovery times, often accompanied by more severe symptoms like sinus congestion and persistent coughs.
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- Within the GI tract, alcohol exposure can also alter the number and abundance of microorganisms present within the microbiome, all of which play an important role in normal GI function.
- This could be because alcohol influences aspects of the immune response.
Inflammation is the source of many serious conditions, but it’s actually your immune system’s way of healing your body after an injury or fighting an infection. When you get a cut or the flu, your body calls in an inflammatory team to handle the situation. The area gets hot, painful, and swollen as your defenses attack the problem. The idea that a hot toddy or a glass of whiskey can alleviate the symptoms of a cold or flu is a persistent cultural notion. The temporary warmth and slight numbing sensation from alcohol can feel comforting, leading many to believe it has medicinal properties.
How does heavy drinking affect the body?
This recommendation takes into account factors such as the risk of infection, blood alcohol concentration, and the dose-dependent manner in which alcohol affects the body. It aligns with guidelines that consider the impact of drinks per day on various aspects of health, including mental health services administration. The combination of impaired defenses and organ dysfunction leaves the body susceptible to numerous health issues. Heavy drinkers seem to be more prone to a wide range of health complications, ranging from respiratory infections to serious liver diseases and beyond. Alcohol, especially when consumed in excessive amounts, can have detrimental effects on multiple aspects of our immune system.

Comparing this phase to other recovery challenges highlights its transient nature. Just as cravings or mood swings often peak early in sobriety, immune adjustments follow a similar pattern. While catching a cold might feel discouraging, it’s a sign your body is healing. Unlike the persistent risks of continued drinking—such as liver damage or increased cancer risk—this heightened susceptibility is short-lived. Viewing it as a step toward better health, rather than a setback, can reframe the experience and reinforce your commitment to recovery. For example, one study found that women who consumed 330 mL of beer for 30 drug addiction days exhibited a significant increase in leukocytes, mature CD3+ T-cells, neutrophils, and basophils.
The Truth About Alcohol and Immunity
It impairs the production and release of immune system cells called cytokines, which are responsible for regulating inflammation and fighting off infections. http://www.chikako-oguma.com/the-effect-of-alcohol-on-our-eyesight-eye-health/ Alcohol also damages the cells lining our respiratory system, making it easier for viruses to invade and cause colds. The negative effects of ethanol lead to alcoholic cirrhosis, where healthy liver tissue is replaced by scar tissue. This impairs liver function, affecting its role in detoxification and metabolism.
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Chronic alcohol intake lowers lymphocyte counts, reduces white blood cell effectiveness, and increases the risk of bacterial and viral infections. (3) Long-term effects alcohol has on the body include slowing tissue repair and increasing the risk of ongoing inflammation. The impact on immune cells and functions contributes to an increased risk of diseases and infections. We can’t stress enough the importance of moderation in consuming alcohol to maintain robust immunity. You don’t have to be a chronic alcoholic in order for your health and immunity to suffer.
The impact on inflammatory pathways can exacerbate existing health problems and create a pro-inflammatory environment. Reducing alcohol intake, or abstaining altogether, is crucial to mitigate inflammation and lower the risk of inflammation-related diseases. Because of those negative effects, people who suffer from an alcohol use disorder (AUD) or drink too much too often are more susceptible to diseases and infections.